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the need for continued investments in vaccine access,
                                                                  diagnostic capacity, and operational readiness. The
                                                                  risk  of resurgence, particularly in  high-burden settings,
                                                                  remains significant.

                                                                  Several initiatives are underway to close the Mpox vaccine
                                                                  gap, including the planned distribution of 50,000 doses,
                                                                  the HERA–Bavarian Nordic partnership securing 215,000
                                                                  doses, and the accelerated WHO EUL process to expand
                                                                  regulatory  access.  Most recently,  Africa CDC  received
                                                                  an additional 110,000 MVA-BN doses from Bavarian
                                                                  Nordic, bringing the company’s total contributions to
                                                                  165,000 doses for Africa. Through the Mpox Access and
                                                                  Allocation Mechanism, these newly donated doses have
                                                                  been allocated to Uganda, one of the most affected
                                                                  countries  in 2025, strengthening  its  outbreak response
                                                                  and improving equitable vaccine access across the
                                                                  continent.

                                                                  While  these  efforts  reflect  growing  momentum,  they
                                                                  also underscore the continued need for sustained
                                                                  financing, regional manufacturing, and fair procurement
                                                                  mechanisms to secure long-term vaccine readiness for
                                                                  Africa.




                                                                  What Can the Public Do?
            important that we respond with calm, informed actions   Public awareness and prevention remain key pillars of
            rather than succumbing to panic or misinformation.”
                                                                  Mpox control. Individuals can reduce their risk by:
                                                                  •        Avoiding close contact with people who have a
                                                                         rash or symptoms consistent with Mpox
            Vaccine Access: A Major Challenge                     •        Practising good hand hygiene, including regular
                                                                         handwashing
            Although the Mpox situation has stabilised in several   •      Seeking medical advice promptly if symptoms
            countries, vaccine access remains one of the most critical   develop
            constraints in sustaining control efforts. At the height of   •     Relying on credible sources of information and
            the outbreak, Africa required an estimated 10 million        avoiding the spread of misinformation
            Mpox vaccine doses, yet only around 20,000 doses were
            initially available. This severe imbalance prompted Africa   Education, early detection, and community engagement
            CDC to declare Mpox a Public Health Emergency of      are essential to breaking chains of transmission.
            Continental Security (PHECS) in August 2024, a historic
            first for the continent.
                                                                  “The focus remains on educating the public,
            Following  months  of  intensified  surveillance,  improved   ensuring access to vaccines, and coordinating
            coordination,  declining  transmission  rates  in  several   a robust international response to contain the
            affected regions, and strengthened national response   outbreak and prevent further spread,”
            capacities, Africa CDC lifted the continental emergency   says Dr Ndwandwe.
            designation on 22 January 2026. However, the decision
            to  remove  the  emergency  status  does  not  diminish



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