The SAMRC was established in 1969 and is dedicated to improving the health of people in South Africa, through research, innovation, development, and technology transfer. The scope of research includes laboratory investigations, clinical research, and public health studies.

We conduct research on South Africa’s quadruple burden of disease: maternal, newborn and child health, HIV/AIDS and TB, non-communicable diseases, and interpersonal violence. Our work is to acquire evidence-based information to inform health policy and practice and improve the quality and health status of people in South Africa. 

We are the largest local funder of health research, medical diagnostics, medical devices, and therapeutics. We are pioneers in cutting-edge medical innovations, focusing on genomic research, novel treatment regimens, vaccine development, diagnostic tools, and the development of new drugs and devices. 

Transformation remains a vital part of developing sustainable health research capacity in South Africa. Through Self-Initiated Research (SIR) grants, the Mid-Career Scientist programme, the Bongani Mayosi National Health Scholars Programme, and other initiatives and platforms, the SAMRC will continue to promote gender, racial, institutional, and geographic parity and enhance our ability to thrive in the 21st century. As a guardian of health research, the SAMRC is fostering a healthy nation through research and innovation.