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South African University and MRC Intramural Flagship Projects  

The MRC announced the winning Flagship Projects, led by some of South Africa’s most accomplished scientists, at a media briefing at the MRC in Cape Town on Wednesday, 30 October 2013.  They are:

No. Institution PI Title
1. Cape Peninsula University of Technology Professor Tandi Matsha Progressive research on risk factors of type 2 diabetes and cardiovascular diseases in South Africa
2 North-West University Professor Richard K Haynes Development to the Clinical Phase of Oxidant and Redox Drug Combinations for Treatment of Malaria, TB and Related Diseases
3. Rhodes University Professor Heinrich Hoppe Integration of bioassay capacity, target identification and multidisciplinary research for the discovery of drug lead compounds
4 Stellenbosch University Professor Soraya Seedat Understanding the SHARED ROOTS of Neuropsychiatric Disorders and Modifiable Risk Factors for Cardiovascular Disease
5. University of Cape Town Professor Robin Wood Tuberculosis Transmission: Host, Bacterium and Environment
6. University of Free State Dr Frederik du Plessis High energy X-ray Beam Advanced Radiation Dosimetry and Verification
7. University of KwaZulu-Natal Professor Tulio de Oliveira A multi-disciplinary approach to understand the causes and consequences of HIV transmission and drug resistance in hyper-epidemic setting in rural South Africa
8. University of Limpopo (MEDUNSA) Professor Akhter Goolam-Mahomed Evaluating a new treatment regimen for patients with extensively drug-resistant TB (XDR-TB) and resistance beyond XDR-TB – a randomised controlled trial
9. University of Pretoria Professor Michael S Pepper Stem cell research and therapy – addressing South Africa’s disease burden
10. University of Western Cape Professor Alan Christoffels Comprehensive Bacterial Analytical ToolKit for Tuberculosis Research
11. University of Witwatersrand Professor Lynn Morris Antiviral properties of HIV vaccine-elicited antibodies
12. Walter Sisulu University Professor Abolade A Awotedu Investigation of the Management of Pericarditis Trial II: A Randomized Comparison of Complete Percutaneous Pericardiocentesis plus Interferon Gamma Testing Versus Empiric Treatment Without Pericardiocentesis in Suspected Tuberculous Pericarditis
13. MRC
Alcohol and Drug Abuse Research Unit
Professor Charles Parry Effectiveness of an alcohol-focused intervention in improving adherence to antiretroviral therapy (ART) and HIV treatment outcomes
14. MRC
Burden of Disease Research Unit
Professor Debbie Bradshaw 2nd South African Comparative Risk Assessment
15. MRC
Centre for Molecular and Cellular Biology
Professor Paul van Helden Improving TB diagnosis and treatment through basic, applied and health systems research
16. MRC
Gender and Health Research Unit
Professor Naeemah Abrahams The impact of rape in women on HIV acquisition and retention linkages to care: a longitudinal study
17. MRC
South African Cochrane Centre
Dr Tamara Kredo South African Guideline Evaluation Project

Contact details
Please direct your requests for information and questions/queries on flagship projects to:
Dr Niresh Bhagwandin
Flagship Projects Coordinator

Strategic Research Initiatives
Tel: +27 21 938 0652; Email:

Ms Arlene Smith
Flagship Projects Administrator
Strategic Research Initiatives
Tel: +27 21 938 0653; Email:

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Last updated:
29 February, 2016
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