Profiling Science

Support for alcohol policies among drinkers in Mongolia, New Zealand, Peru, South Africa, St Kitts and Nevis, Thailand and Vietnam: Data from the international alcohol control study
Parry CDH, Londani M, Enkhtuya P, Huckle T, Piazza M, Gray-Phillip G, Chaiyasong S, Viet Cuong P, Casswell S
https://www.ncbi.nlm.nih.gov/pubmed/29266725
/research-for-our-people/support-alcohol-policies-among-drinkers-mongolia-new-zealand-peru-south
Rotavirus strain diversity in eastern and southern African countries before and after vaccine introduction
Seheri LM, Magagula NB, Peenze I, Rakau K, Ndadza A, Mwenda JM, Weldegebriel G, Steele AD, Mphahlele MJ
https://www.sciencedirect.com/science/article/pii/S0264410X17316791
/research-for-our-people/rotavirus-strain-diversity-eastern-and-southern-african-countries-and-after
Describing objectively measured physical activity levels, patterns, and correlates in a cross sectional sample of infants and toddlers from South Africa
Prioreschi A, Brage S, Hesketh KD, Hnatiuk J, Westgate K, Micklesfield LK
https://www.ncbi.nlm.nih.gov/pubmed/29273035
/research-for-our-people/describing-objectively-measured-physical-activity-levels-patterns-and
APP-supported promotion of child growth and development by community health workers in Kenya: Feasibility and acceptability study
van Heerden A, Sen D, Desmond C, Louw J, Richter L
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736876/
/research-for-our-people/app-supported-promotion-child-growth-and-development-community-health
Burden of respiratory syncytial virus infection in South African HIV-infected and HIV-uninfected pregnant and post-partum women: A longitudinal cohort study
Madhi SA, Cutland CL, Downs S, Jones S, van Niekerk N, Simoes EAF, Nunes MC
https://www.ncbi.nlm.nih.gov/pubmed/29253090
/research-for-our-people/burden-respiratory-syncytial-virus-infection-south-african-hiv-infected-and
Exchange transfusions for extreme hypertriglyceridemia in a 7-week-old infant with multi-organ failure
Ghoor S, Berlyn P, Brey N
https://www.ncbi.nlm.nih.gov/pubmed/29174071
/research-for-our-people/exchange-transfusions-extreme-hypertriglyceridemia-7-week-old-infant-multi
A systematic review of the efficacy and safety of intrapericardial fibrinolysis in patients with pericardial effusion
Wiyeh AB, Ochodo EA, Wiysonge CS, Kakia A, Awotedu AA, Ristic A, Mayosi BM
https://www.ncbi.nlm.nih.gov/pubmed/29107356
/research-for-our-people/systematic-review-efficacy-and-safety-intrapericardial-fibrinolysis-patients
Exome sequencing identifies a novel MAP3K14 mutation in recessive atypical combined immunodeficiency
Schlechter N, Glanzmann B, Hoal EG, Schoeman M, Petersen BS, Franke A, Lau YL, Urban M, van Helden PD, Esser MM, Moller M, Kinnear C
https://www.ncbi.nlm.nih.gov/pubmed/29230214
/research-for-our-people/exome-sequencing-identifies-novel-map3k14-mutation-recessive-atypical
Interleukin-4 Receptor Alpha: From innate to adaptive immunity in murine models of cutaneous leishmaniasis
Hurdayal R, Brombacher F
https://www.ncbi.nlm.nih.gov/pubmed/29176972
/research-for-our-people/interleukin-4-receptor-alpha-innate-adaptive-immunity-murine-models
Neuroimaging genomics in psychiatry-a translational approach. Genome Medicine
Mufford MS, Stein DJ, Dalvie S, Groenewold NA, Thompson PM, Jahanshad N.
https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-017-0496-z
/research-for-our-people/neuroimaging-genomics-psychiatry-translational-approach-genome-medicine
Reduction of in utero lead exposures in South African populations: Positive impact of unleaded petrol
Rollin HB, Olutola B, Channa K, Odland JO
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0186445
/research-for-our-people/reduction-utero-lead-exposures-south-african-populations-positive-impact
Spatial distribution of extensively drug-resistant tuberculosis (XDR TB) patients in KwaZulu-Natal, South Africa
Kapwata T, Morris N, Campbell A, Mthiyane T, Mpangase P, Nelson KN, Allana S, Brust JCM, Moodley P, Mlisana K, Gandhi NR, Shah NS
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181797
/research-for-our-people/spatial-distribution-extensively-drug-resistant-tuberculosis-xdr-tb-patients
Point-of-care chest ultrasound in South African children with suspected pulmonary tuberculosis
Heuvelings CC, Belard S, Andronikou S, Jamieson-Luff N, Grobusch M, Zar H.
http://onlinelibrary.wiley.com/doi/10.1111/tmi.12978/epdf
/research-for-our-people/point-care-chest-ultrasound-south-african-children-suspected-pulmonary
Innovation at the intersection of alcohol and HIV research
van Heerden A, Tomlinson M, Skeen S, Parry C, Bryant K, Rotheram-Borus MJ.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660130/
/research-for-our-people/innovation-intersection-alcohol-and-hiv-research
High prevalence of HIV and Non-Communicable Disease (NCD) risk factors in rural KwaZulu-Natal, South Africa
van Heerden A, Barnabas RV, Norris SA, Micklesfield LK, van Rooyen H, Celum C.
http://onlinelibrary.wiley.com/doi/10.1002/jia2.25012/abstract
/research-for-our-people/high-prevalence-hiv-and-non-communicable-disease-ncd-risk-factors-rural
Is 24-hour central blood pressure superior to 24-hour brachial blood pressure for predicting organ damage?
Schutte AE, Laurent S.
http://hyper.ahajournals.org/content/early/2017/10/20/HYPERTENSIONAHA.117.10024
/research-for-our-people/24-hour-central-blood-pressure-superior-24-hour-brachial-blood-pressure
Financial arrangements for health systems in low-income countries: An overview of systematic reviews
Wiysonge CS, Paulsen E, Lewin S, Ciapponi A, Herrera CA, Opiyo N, Pantoja T, Rada G, Oxman AD
https://www.ncbi.nlm.nih.gov/pubmed/28891235
/research-for-our-people/financial-arrangements-health-systems-low-income-countries-overview
The association between elevated blood lead levels and violent behavior during late adolescence: The South African Birth to Twenty Plus cohort
Nkomo P, Mathee A, Naicker N, Galpin J, Richter LM, Norris SA
https://www.ncbi.nlm.nih.gov/pubmed/28916132
/research-for-our-people/association-between-elevated-blood-lead-levels-and-violent-behavior-during
Women's and men's reports of past-year prevalence of intimate partner violence and rape and women's risk factors for intimate partner violence: A multicountry cross-sectional study in Asia and the Pacific
Jewkes R, Fulu E, Tabassam Naved R, Chirwa E, Dunkle K, Haardorfer R, Garcia-Moreno C
http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002381
/research-for-our-people/womens-and-mens-reports-past-year-prevalence-intimate-partner-violence-and
IL-4-producing B cells regulate T helper cell dichotomy in type 1- and type 2-controlled diseases
Hurdayal R, Ndlovu HH, Revaz-Breton M, Parihar SP, Nono JK, Govender M, Brombacher F
https://www.ncbi.nlm.nih.gov/pubmed/28916732
/research-for-our-people/il-4-producing-b-cells-regulate-t-helper-cell-dichotomy-type-1-and-type-2
Nine-valent human papillomavirus vaccine: Great science, but will it save lives?
Denny L
https://www.ncbi.nlm.nih.gov/pubmed/28886906
/research-for-our-people/nine-valent-human-papillomavirus-vaccine-great-science-will-it-save-lives
Protein Kinase C-Delta (PKCDELTA), a marker of inflammation and tuberculosis disease progression in humans, is important for optimal macrophage killing effector functions and survival in mice
Parihar SP, Ozturk M, Marakalala MJ, Loots DT, Hurdayal R, Beukes D, Van Reenen M, Zak DE, Mbandi SK, Darboe F, Penn-Nicholson A, Hanekom WA, Leitges M, Scriba TJ, Guler R, Brombacher F.
https://www.ncbi.nlm.nih.gov/pubmed/28832027
/research-for-our-people/protein-kinase-c-delta-pkcdelta-marker-inflammation-and-tuberculosis-disease
Cohort profile: The Siyakhula Cohort, rural South Africa
Rochat TJ, Houle B, Stein A, Pearson RM, Newell ML, Bland RM
https://www.ncbi.nlm.nih.gov/pubmed/29025088
/research-for-our-people/cohort-profile-siyakhula-cohort-rural-south-africa
The Amagugu intervention for disclosure of maternal HIV to uninfected primary school-aged children in South Africa: A randomised controlled trial
Rochat TJ, Stein A, Cortina-Borja M, Tanser F, Bland RM
https://www.ncbi.nlm.nih.gov/pubmed/28843988
/research-for-our-people/amagugu-intervention-disclosure-maternal-hiv-uninfected-primary-school-aged
Socioeconomic differences in mortality in the antiretroviral therapy era in Agincourt, rural South Africa, 2001-13: A population surveillance analysis
Kabudula CW, Houle B, Collinson MA, Kahn K, Gomez-Olive FX, Tollman S, Clark SJ
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559644/
/research-for-our-people/socioeconomic-differences-mortality-antiretroviral-therapy-era-agincourt
Mortality and socioeconomic status: The vicious cycle between poverty and ill health.
Pillay-van Wyk V, Bradshaw D
http://www.thelancet.com/journals/langlo/article/PIIS2214-109X(17)30304-2/fulltext
/research-for-our-people/mortality-and-socioeconomic-status-vicious-cycle-between-poverty-and-ill
Comparison of traditional culture and molecular QPCR for detection of simultaneous carriage of multiple pneumococcal serotypes in African children
Olwagen CP, Adrian PV, Madhi SA
https://www.ncbi.nlm.nih.gov/pubmed/28680083
/research-for-our-people/comparison-traditional-culture-and-molecular-qpcr-detection-simultaneous
Susceptibility of mycobacterium tuberculosis cytochrome bd oxidase mutants to compounds targeting the terminal respiratory oxidase, cytochrome c
Moosa A, Lamprecht DA, Arora K, Barry CE 3rd, Boshoff HIM, Ioerger TR, Steyn AJC, Mizrahi V, Warner DF.
https://www.ncbi.nlm.nih.gov/pubmed/28760899
/research-for-our-people/susceptibility-mycobacterium-tuberculosis-cytochrome-bd-oxidase-mutants
Cochrane corner: Beta-blockers for hypertension
Wiysonge CS, Bradley HA, Volmink J, Mayosi BM.
http://heart.bmj.com/content/early/2017/07/29/heartjnl-2017-311585
/research-for-our-people/cochrane-corner-beta-blockers-hypertension
The cross-national epidemiology of social anxiety disorder: Data from the world mental health survey initiative
Stein DJ, Lim CCW, Roest AM, de Jonge P, Aguilar-Gaxiola S, Al-Hamzawi A, Alonso J, Benjet C, Bromet EJ, Bruffaerts R, de Girolamo G, Florescu S, Gureje O, Haro JM, Harris MG, He Y, Hinkov H, Horiguchi I, Hu C, Karam A, Karam EG, Lee S, Lepine JP, Navarro-Mateu F, Pennell BE, Piazza M, Posada-Villa J, Ten Have M, Torres Y, Viana MC, Wojtyniak B, Xavier M, Kessler RC, Scott KM
https://www.ncbi.nlm.nih.gov/pubmed/28756776
/research-for-our-people/cross-national-epidemiology-social-anxiety-disorder-data-world-mental-health
Advances in the diagnosis of pneumonia in children
Zar HJ, Andronikou S, Nicol MP
http://www.bmj.com/content/358/bmj.j2739
/research-for-our-people/advances-diagnosis-pneumonia-children
Living arrangements, disability and gender of older adults among rural South Africa
Schatz E, Ralston M, Madhavan S, Collinson MA, Gomez-Olive FX
https://www.ncbi.nlm.nih.gov/pubmed/28651372
/research-for-our-people/living-arrangements-disability-and-gender-older-adults-among-rural-south
Sugary beverage taxation in South Africa: Household expenditure, demand system elasticities, and policy implications
Stacey N, Tugendhaft A, Hofman K.
https://www.ncbi.nlm.nih.gov/pubmed/28579502
/research-for-our-people/sugary-beverage-taxation-south-africa-household-expenditure-demand-system
Interleukin-4 receptor alpha is still required after Th2 polarization for the maintenance and the recall of protective immunity to Nematode infection
Nono JK, Ndlovu H, Abdel Aziz N, Mpotje T, Hlaka L, Brombacher F.
http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005675
/research-for-our-people/interleukin-4-receptor-alpha-still-required-after-th2-polarization
The protective role of oestradiol against silent myocardial ischemia and hypertension risk in South African men: The SABPA study
Malan NT, von Känel R, Steyn HS, Kruger R, Malan L.
https://www.ncbi.nlm.nih.gov/pubmed/28629624
/research-for-our-people/protective-role-oestradiol-against-silent-myocardial-ischemia-and
Changes in host immune-endocrine relationships during tuberculosis treatment in patients with cured and failed treatment outcomes
Kleynhans L, Ruzive S, Ehlers L, Thiart L, Chegou NN, Conradie M, Kriel M, Stanley K, van der Spuy GD, Kidd M, van Helden PD, Walzl G, Ronacher K.
https://www.ncbi.nlm.nih.gov/pubmed/28674532
/research-for-our-people/changes-host-immune-endocrine-relationships-during-tuberculosis-treatment
Efficacy of maternal influenza vaccination against all-cause lower respiratory tract infection hospitalizations in young infants: Results from a randomized controlled trial
Nunes MC, Cutland CL, Jones S, Downs S, Weinberg A, Ortiz JR, Neuzil KM, Simoes EAF, Klugman KP, Madhi SA
https://www.ncbi.nlm.nih.gov/pubmed/28575286
/research-for-our-people/efficacy-maternal-influenza-vaccination-against-all-cause-lower-respiratory
The incremental value of repeated induced sputum and gastric aspirate samples for the diagnosis of pulmonary tuberculosis in young children with acute community-acquired pneumonia
Moore DP, Higdon MM, Hammitt LL, Prosperi C, DeLuca AN, Da Silva P, Baillie VL, Adrian PV, Mudau A, Deloria Knoll M, Feikin DR, Murdoch DR, O'Brien KL, Madhi SA.
https://www.ncbi.nlm.nih.gov/pubmed/28575364
/research-for-our-people/incremental-value-repeated-induced-sputum-and-gastric-aspirate-samples
Diagnosis of pulmonary tuberculosis in HIV-infected and uninfected children using Xpert MTB/RIF ultra
Zar HJ, Workman L, Nicol MP.
http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2017.195.1_MeetingAbstracts.A7610
/research-for-our-people/diagnosis-pulmonary-tuberculosis-hiv-infected-and-uninfected-children-using
Safety and immunogenicity of a parenteral P2-VP8-P[8] subunit rotavirus vaccine in toddlers and infants in South Africa: A randomised, double-blind, placebocontrolled trial
Groome MJ, Koen A, Fix A, Page N, Jose L, Madhi SA, McNeal M, Dally L, Cho I, Power M, Flores J, Cryz S.
https://www.ncbi.nlm.nih.gov/pubmed/28483414
/research-for-our-people/safety-and-immunogenicity-parenteral-p2-vp8-p8-subunit-rotavirus-vaccine
Psychiatric practice: Caring for patients, collaborating with partners, or marketing to consumers?
Stein DJ.
https://www.ncbi.nlm.nih.gov/pubmed/28498586
/research-for-our-people/psychiatric-practice-caring-patients-collaborating-partners-or-marketing
Assessing the complexity of interventions within systematic reviews: Development, content and use of a new tool (iCAT-SR). BMC Medical Research Methodology
Lewin S, Hendry M, Chandler J, Oxman AD, Michie S, Shepperd S, Reeves BC, Tugwell P, Hannes K, Rehfuess EA, Welch V, McKenzie JE, Burford B, Petkovic J, Anderson LM, Harris J, Noyes J.
https://www.ncbi.nlm.nih.gov/pubmed/28446138
/research-for-our-people/assessing-complexity-interventions-within-systematic-reviews-development
Age-dependent development of left ventricular wall thickness in type 2 diabetic (db/db) mice is associated with elevated low-density lipoprotein and triglyceride serum levels
Dludla PV, Essop MF, Gabuza KB, Muller CJ, Louw J, Johnson R.
https://www.ncbi.nlm.nih.gov/pubmed/28393273
/research-for-our-people/age-dependent-development-left-ventricular-wall-thickness-type-2-diabetic
Targeting the aryl hydrocarbon receptor nuclear translocator complex with DMOG and Stemregenin 1 improves primitive hematopoietic stem cell expansion
Jackson CS, Durandt C, Janse van Rensburg I, Praloran V, Brunet de la Grange P, Pepper MS.
https://www.ncbi.nlm.nih.gov/pubmed/28445828
/research-for-our-people/targeting-aryl-hydrocarbon-receptor-nuclear-translocator-complex-dmog-and
Immunization with 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) according to different schedules in infants in South Africa: A phase III trial
Madhi SA, Koen A, Jose L, Moreira M, van Niekerk N, Cutland C, François N, Ruiz-Guiñazú J, Yarzabal JP, Borys D, Schuerman L.
https://www.ncbi.nlm.nih.gov/pubmed/28425818
/research-for-our-people/immunization-10-valent-pneumococcal-non-typeable-haemophilus-influenzae
Sustained inhibition of HBV replication in vivo after systemic injection of AAVs encoding artificial antiviral primary microRNAs
Maepa MB, Ely A, Grayson W, Arbuthnot P.
http://www.cell.com/molecular-therapy-family/nucleic-acids/pdfExtended/S2162-2531(17)30157-9
/research-for-our-people/sustained-inhibition-hbv-replication-vivo-after-systemic-injection-aavs
Impact of CYP2D6 genotype on amitriptyline efficacy for the treatment of diabetic peripheral neuropathy: A pilot study
Chaudhry M, Alessandrini M, Rademan J, Dodgen TM, Steffens FE, van Zyl DG, Gaedigk A, Pepper MS
https://www.ncbi.nlm.nih.gov/pubmed/28350251
/research-for-our-people/impact-cyp2d6-genotype-amitriptyline-efficacy-treatment-diabetic-peripheral
Recent advances in understanding hypertension development in sub-Saharan Africa
Schutte AE, Botha S, Fourie CM, Gafane-Matemane LF, Kruger R, Lammertyn L, Malan L, Mels CM, Schutte R, Smith W, van Rooyen JM, Ware LJ, Huisman HW.
https://www.ncbi.nlm.nih.gov/labs/articles/28332510/
/research-for-our-people/recent-advances-understanding-hypertension-development-sub-saharan-africa
Psychosocial group interventions to improve psychological well-being in adults living with HIV
van der Heijden I, Abrahams N, Sinclair D.
https://www.ncbi.nlm.nih.gov/pubmed/28291302
/research-for-our-people/psychosocial-group-interventions-improve-psychological-well-being-adults
Efficacy and safety of agomelatine (10 or 25 mg/day) in non-depressed out-patients with generalized anxiety disorder: A 12-week, double-blind, placebo-controlled study
Stein DJ, Ahokas A, Jarema M, Avedisova AS, Vavrusova L, Chaban O, Gruget C, Olivier V, Picarel-Blanchot F, de Bodinat C.
https://www.ncbi.nlm.nih.gov/pubmed/28298261
/research-for-our-people/efficacy-and-safety-agomelatine-10-or-25-mgday-non-depressed-out-patients
Cookstove options for safety and health: Comparative analysis of technological and usability attributes
Kimemia D, Van Niekerk A.
http://www.sciencedirect.com/science/article/pii/S0301421517301659
/research-for-our-people/cookstove-options-safety-and-health-comparative-analysis-technological-and