Request for Applications Pharmacogenomics in Precision Medicine

Call for Proposals Release date Deadline date
MRC-RFA-SHIP 01-2019

Pharmacogenomics in Precision Medicine

30 September 2019
5 November 2019 (midnight SAST)

Target audience: Open call for researchers based at South African universities, science councils (including the SAMRC) and other public research organizations.

Topics: Pharmacogenomics in Precision Medicine

The SAMRC, through its Strategic Health Innovation Partnership (SHIP) programme, is seeking to fund five highly collaborative projects in the areas of pharmacogenomics with reference to failure of treatments with drugs (or drug classes) for Non-Communicable diseases, specifically Hypertension, Cardiovascular, Diabetes and Cancer in (South) Africa. This Request for Applications (RFA) is an open call for researchers based in South African public research institutions, who are conducting research focusing on: 

  • Extending foundational studies in pharmacogenomics to incorporate whole and partial genome sequence activities and other deep resequencing efforts to understand treatment failure of specific drugs for the above-mentioned diseases;
  • Making novel discoveries aimed at the molecular-level to understand fundamental biological and cellular processes that determine drug responses in African populations;
  • Acquiring mechanistic understanding from and apply comprehensive information sets to understand treatment failure with the goal of being able to use this data to predict responsiveness in other population groups;
  • Seek to contribute to the building of a South African Genetic database.

The intent of this RFA is to support collaborative research that will advance the respective fields towards new products or solutions to address for Non-Communicable diseases, specifically Hypertension, Cardiovascular, Diabetes and Cancer in (South) Africa, with a focus on harnessing the core scientific strengths and areas of advantage in the country.

The SAMRC-SHIP has approved a total budget of R 12-14 million to fund eligible projects (at a maximum value of R3 million per project) for up to 3 years.

Proposals will only be considered for funding if they meet the funding eligibility requirements as specified in the RFA document.

All applications must be submitted on the SAMRC templates. Please see the links below for the relevant application documents. 

Application documents:

Expiration: 
Tuesday, November 5, 2019 - 23:59