TB Epidemiology and Intervention Research Unit

Outputs 2002 - 2004

Publications

1. Weyer K , Levin J, Lancaster JL, Fourie PB. DOTSPacks for improved tuberculosis treatment delivery in South Africa. (Submitted).
2. Weyer K , Levin J, Brand J, Lancaster JL, Van der Walt M. Finding cases among persons suspected of having tuberculosis: high yields in South Africa (Submitted).
3. Van der Walt M , Weyer K, Kantor P and the DOTSPlus Study Group of SA.. Ethical and legal dilemmas around management of multidrug-resistant tuberculosis patients in South Africa (Submitted).
4. Weyer K , Levin J, Brand J, Lancaster J, Van der Walt M, Weber L. HIV-associated tuberculosis in South Africa: results from a national survey using sputum investigations (Submitted).
5. Van der Walt M , Weyer K, Levin J. Transfer and treatment interruption patterns among tuberculosis patients in South Africa. (Submitted).
6. Weyer K . DOTS-Plus for multidrug-resistant tuberculosis patients in South Africa. Cont MedEduc (in press).
7. Laserson KF, Binkin NJ, Thorpe LE, Laing R, Iademarco MF, Bloom A, Agerton TB, Nelson L, Cegielski JP, Ferroussier O, Holtz T, Vitek E, Gammino V, Tan K, Aquino K, Weyer K, Sy DN, Vernon A, Becetta J, Ershava J, Wells CD. Capacity building for international tuberculosis control through operations research training. Int J Tuberc Lung Dis (in press).
8. Weyer K , Van der Walt M, Levin J, Lancaster J, Brand J and the DOTSPlus Group of SA. Standardised management of multidrug-resistant tuberculosis in South Africa: results from the first cohort of patients treated under control programme conditions N Eng J (in press).
9. Weyer K , Levin J, Brand J, Lancaster JL, Van der Walt M. Drug-resistant tuberculosis and its determinants in South Africa Int J Tuberc Lung Dis (in press).
10. Laserson K, Thorpe L, Weyer K, Mitnick C, Riekstina V, Zarovska E, Rich M, Fraser H, Alarcon E, Cegielski P, Grzemska M, Gupta R, Espinal M. Speaking the same language: treatment outcome definitions for multidrug-resistant tuberculosis. Int J Tuberc Lung Dis (in press).
11. Fourie PB, Lancaster J, Weyer K, Beyers N. High prevalence and annual risk of tuberculosis infection in an urban community in Cape Town, South Africa. Int J Tuberc Lung Dis (in press).
12. K Weyer . Multidrug-resistant tuberculosis. In: Management of Tuberculosis. Foundation for Professional Development, Medical Association of SA: Pretoria, 2004.
13. K Weyer , L Mvusi. Transmission and pathogenesis of tuberculosis. In: Management of Tuberculosis. Foundation for Professional Development, Medical Association of SA: Pretoria, 2004.
14. K Weyer , R Matji. Epidemiology and control of tuberculosis. In: Management of Tuberculosis. Foundation for Professional Development, Medical Association of SA: Pretoria, 2004.
15. K Weyer , R Matji. Tuberculosis treatment. In: Management of Tuberculosis. Foundation for Professional Development, Medical Association of SA: Pretoria, 2004.
16. K Weyer (ed) Management of Tuberculosis. Foundation for Professional Development, Medical Association of SA: Pretoria, 2004, 302 pages.
17. World Health Organization. Anti-Tuberculosis Drug Resistance in the World. Third Global Report. The WHO/IUATLD Global Project on Anti-Tuberculosis Drug Resistance Surveillance 1999-2002. WHO: Geneva, 2004. 128 pages (K Weyer – Member of Writing Committee).
18. Weyer K . Tuberculosis and HIV in Southern Africa. African Health Care Journal 2003; 2: 6-9.
19. Aziz MA, Fatoumata B, Becx-Bleumink M, Bretzel G, Humes R, Iademarco MF, Kim SJ, Lamothe F, Paramasivan CN, Ridderhof J, Sloutsky A, Van Deun A, Vohra-Shah K, Weyer K. External Quality Assessment for AFB Smear Microscopy. APHL: Washington, 2002, 111 pages ( K Weyer – WHO representative and Member of Writing Committee).
20. WHO/IUATLD Working Group on Anti-tuberculosis Drug Resistance Surveillance. Quality assurance programme for drug susceptibility testing of Mycobacterium tuberculosis in the WHO/IUATLD Supranational Laboratory Network: five rounds of proficiency testing 1994-1998. Int J Tuberc Lung Dis 2002; 6(9): 748-756. ( K Weyer – Contributor as Head of SRL for Africa).

Policy documents

1. Weyer K, Van der Walt M, Kantor P. Managing Multidrug-Resistant Tuberculosis. Legal implications. MRC Policy brief (1) Jan 2005
2. Weyer K , Van der Walt M, Lancaster J. DOTS-Plus for StandardisedManagement of Multidrug-resistant (MDR) Tuberculosis Patients in South Africa. 3 rd Ed. Pretoria: Directorate TB Control, Department of Health, 2004.
3. Kantor P, Van der Walt M, Weyer K. Legal Issues in Management of Multidrug-resistant (MDR) Tuberculosis Patients in South Africa . Pretoria: Medical Research Council, 2004 (Department of Health Policy Document).
4. Van der Walt M , Weyer K, Kantor P. Legal Dilemmas in Management of Multidrug-resistant Tuberculosis in South Africa. Pretoria: Medical Research Council, 2004 (MRC Policy Brief).
5. Weyer K. Performance Standards for Tuberculosis Laboratory Services in South Africa. Pretoria: Medical Research Council, 2003.

Dissertations/Theses

1. TN Maguga. Rapid molecular prediction of drug resistance in Mycobacterium tuberculosis in the Limpopo Province of South Africa. MSc, University of the North (Co-supervisor K Weyer).

Conference presentations

1. Weyer K , Levin J. Implementation and management of operational research training. Presented at: 35 th World Conference on Lung Health of the International Union Against Tuberculosis and Lung Disease, Paris, France. October 2004 (invited paper).
2. Weyer L , Brand J. Importance of proficiency testing at regional laboratory network level. Presented at: 35 th World Conference on Lung Health of the International Union Against Tuberculosis and Lung Disease, Paris, France. October 2004 (invited paper).
3. Weyer K , Van der Walt M, Lancaster J, Brand J, Levin J. Treatment protocols and outcomes using a standardised treatment regimen for multidrug-resistant tuberculosis in South Africa. Presented at: 35 th World Conference on Lung Health of the International Union Against Tuberculosis and Lung Disease, Paris, France. October 2004 (invited paper).
4. Weyer K . Multidrug-resistant tuberculosis and HIV in South Africa. Presented at: Annual Meeting of the Tuberculosis Surveillance Research Unit, Geneva, Switzerland, April 2004 (invited paper).
5. Weyer K . Standardised management of MDR-TB in South Africa. Presented at: Annual Meeting of the Tuberculosis Surveillance Research Unit, Geneva, Switzerland, April 2004 (invited paper).
6. Weyer K . Multidrug-resistant tuberculosis in South Africa. Presented at: Annual Conference of the South African National Tuberculosis Association, Durban, South Africa. August 2003 (Key-note address).
7. Weyer K , Van der Walt M, Lancaster J. MDR-TB in South Africa: New strategies and policies. Presented at: Conference on tuberculosis control: a multidisciplinary approach to research, policy and practice. Bloemfontein, South Africa. November 2003 (invited paper).
8. Weyer K . Laboratory safety: balancing service with worker protection. Presented at: 34 th World Conference on Lung Health of the International Union Against Tuberculosis and Lung Disease, Paris, France. October 2003 (invited paper).
9. Weyer K . Culture and identification of Mycobacterium tuberculosis. Presented at: 34 th World Conference on Lung Health of the International Union Against Tuberculosis and Lung Disease, Montréal, Canada. October 2003 (invited paper).
10. Weyer K , Levin J, Van der Walt M, Brand J, Lancaster J. MDR-TB management in South Africa. Presented at: Meeting of the WHO DOTSPlus Working Group on MDR-TB, Paris, France. October 2003 (invited paper).
11. Weyer K , Levin J, Van der Walt M, Brand J, Lancaster J. Standardised management of multidrug-resistant tuberculosis (MDR-TB) patients in South Africa. Presented at: Annual Conference of the American Thoracic Society, Seattle, USA. May 2003 (invited paper).
12. Weyer K . MDR-TB in South Africa. Presented at: 14 th Conference of IUATLD Africa Region, Durban, South Africa. June 2002 (invited paper).

Conference abstracts

1. Wong ML, Weyer K. Demographics, presenting features and drug susceptibilities in a cohort of patients with tuberculosis. Presented at: South African Thoracic Society Conference, Durban, August 2004 (poster).
2. Findlay A, Van der Walt M, Holtz T, Thorpe L, Wells C, Weyer K. Treatment outcomes of patients with multidrug-resistant tuberculosis in South Africa using a standardized regimen 1999 – 2000. Presented at: Infectious Diseases Society Conference, Boston, July 2004 (poster).
3. Austin J, Tsiouris S, Lancaster J, Coetzee D, Weyer K, Stein Z, Toro P, El-Sadr W. A survey of latent TB infection in primary school children in Gugulethu, Cape Town: lessons learned. Presented at: American Thoracic Society Congress, San Diego, USA, May 2004 (poster).
4. Weyer K , Lancaster J, Levin J. DOTSPacks for improved tuberculosis treatment delivery in South Africa (poster). 34 th World Conference on Lung Health of the IUATLD, Paris, France, October 2003 (poster).
5. Leimane V, Weyer K, Laserson KF, Thorpe L, Mitnick CD, Riekstina V, Zarovska E, Rich M, Fraser H, Alarcon E, Cegielski P, Grzemska M, Gupta R, Espinal M. Speaking the same language: proposed treatment outcome definitions for multidrug-resistant tuberculosis. Proceedings of the 33 rd World Conference on Lung Health of the IUATLD, Montréal, Canada, October 2001. Int J Tuberc Lung Dis 2002; 6(10) (Suppl 1): S137 (poster).
6. Weyer K , Lancaster J, Van der Walt M and the DOTSPlus Study Group of South Africa. DOTSPlus for multidrug-resistant (MDR) tuberculosis in South Africa: Results from the first cohort of patients treated with a standardised regimen under tuberculosis control programme conditions. Int J Tuberc Lung Dis 2002; 6(10) (Suppl 1): S138 (poster).