Immunology of Infectious Disease Research Unit

Publications

Publications (2005/2006)

1. Arras M, Louahed J, Heilier JF, Delos M, Brombacher F, Renauld JC, Lison D, Huaux F. (2005). IL-9 Protects against Bleomycin-Induced Lung Injury: Involvement of Prostaglandins. Am J Pathol.166(1):107-15. (I.F. = 8)
2. Arendse, B., Van Snick, J., & Brombacher F. (2005). Interleukin-9 is a susceptibility factor in Leishmania major infection by promoting detrimental Th2/type2 responses. J. Immunol. 174:2205-2211. (I.F.= 7.4).
3. Brys, L., A. Beschin, G. Raes, G.G. Hassanzadeh, W. Noël, J. Brandt, F. Brombacher, P. De Baetselier. (2005). Reactive Oxygen Species and 12/15-lipoxygenase contribute to the anti-proliferative capacity of alternatively activated myeloid cells elicited during helminth infection. J. Immunol., 174:6095-6104. (I.F.= 7.4).
4. Couper KN, RS. Phillips, F. Brombacher, J. Alexander (2005). Parasite-specific IgM plays a significant role in the protective immune response to asexual erythrocytic stage Plasmodium chabaudi AS infection. Parasite Immunol. 27:171-80. (I.F. ca 1.5).
5. Drennan, M., B. Stijlemans, J. Van Den Abbeele, V. Quesniaux, F. Brombacher, P. De Baetselier, B. Ryffel & S. Magez. (2005). The induction of a type 1 response following a Trypanosoma brucei infection is MyD88-dependent. J. Immunol. 175: p. 2501-2509 (I.F. = 7.4)
6. Kuperman, D.A., X. Huang, L. Nguyenvu, C. Hölscher, F. Brombacher & D.J. Erle (2005).IL-4 receptor signaling in Clara cells is required for allergen-induced mucus production. J. Immunol. 175:3746-52 (I.F.= 7.4).
7. Couper KN, Roberts CW, Brombacher F, Alexander J, Johnson LL. (2005) Toxoplasma gondii-specific immunoglobulin M limits parasite dissemination by preventing host cell invasion. Infect Immun. 73:8060-8. (I.F.= 3.7).
8. Cutler, A. & F. Brombacher (2005) Cytokine Therapy. Ann NY Acad Sci. 1056:16-29. (I.F. 1.5)
9. Hölscher, C., B. Arendse, A. Schwegmann, Elmarie Myburgh & F. Brombacher (2006). Impairment of alternative macrophage activation delays cutaneous leishmaniasis in non-healing BALB/c mice. J. Immunol. 176:1115-21 (I.F. = 7.4).
10. Pace, L., S. Rizzo, C. Palombi, F. Brombacher, G. Doria. (2006). IL-4-induced protection of CD4+CD25- Th cells from CD4+CD25+ regulatory T cell-mediated suppression. J. Immunol. 176:3900-04. (I.F.= 7.4).
11. G. Hassanzadeh, P. De Baetselier, L. Brys, W. Noël, J. A. Van Ginderachter, S. Meerschaut, A. Beschin, F. Brombacher and G. Raes (2006). Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo during different pathologies. Blood, in press. (I.F. = 11)
12. Magez S, Radwanska M, Drennan M, Fick L, Baral TN, Brombacher F, Baetselier PD. (2006). Interferon- gamma and Nitric Oxide in Combination with Antibodies Are Key Protective Host Immune Factors during Trypanosoma congolense Tc13 Infections. J Infect Dis.193:1575-1583. (I.F. = 5.5)
13. Nieuwenhuizen, N., A. L. Lopata, M. F. Jeebhay, D. R. Herbert, T. G.Robins, F. Brombacher (2006). The nematode Anisakis, hidden in fish, can cause occupational allergy. J Allergy Clin Immun, 117:1098. (I.F. = 9)
14. Balic A, Harcus YM, Taylor MD, Brombacher F, Maizels RM. (2006). IL-4R signaling is required to induce IL-10 for the establishment of Th2 dominance. Int Immunol., 18:1421-31.
15. Michels, C., P. Goyal, N. Nieuwenhuizen and F. Brombacher (2006). Infection with Syphacia obvelata (pinworm) induces protective Th2 immune responses and influences Ovalbumin-induced allergic reactions. Inf. & Immun. 74:5926-32.
16. Misson P, Brombacher F, Delos M, Lison D, Huaux FA. (2006). Type-2 immune response associated with silicosis is not instrumental in the development of the disease. Am J Physiol Lung Cell Mol Physiol. Sep 22; [Epub ahead of print]
17. G. Galina, L. Dolcetti, P. Serafini, C. De Santo, I. Marigo, M.P. Colombo, G. Basso, F. Brombacher, I. Borrello, P. Zanoveilo,  S. Bicciato, V. Bronte (2006). Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J. Clin. Invest., 116:2777
18. Leeto, M., D. R. Herbert, R. Mariller, A. Schwegmann, L. Fick, and F. Brombacher (2006). CD4+ T cell specific IL-4Ra deficient mice develop exacerbated granulomatous pathology in response to S. mansoni eggs. J. American Pathology. 169:1701-12.

Invited Plenary/Keynote addresses (2005/2006)

2007

• Keynote Speaker at the World Immunology conference in Rio D’ Janeiro, Brasilia (agreed)
• Keynote Speaker at the Howard Hughes workshop in Buenos Aires, Argentina (agreed)
• Plenary Speaker at the Keystone Symposia, USA (agreed)
• Keynote Speaker at the workshop of the Mexican Society for Immunology and Parasitology in Mexico City, Mexico

2006

• Keynote speaker at the workshop of the Immunology Society in Hamburg, Germany
• Keynote speaker at the International Society for Parasitology (ICOPA), Glasgow, Scotland, UK
• Keynote speaker at the Swiss society for Allergology and Immunology (SGAI), Zurich, Switzerland.

2005

• Plenary speaker at the Spring Meeting of the British Parasitology Society, Nottingham, UK.
• Plenary speaker at the opening conference IIDMM, UCT, South Africa

Awards, Bursary, Honours (2005/2006)

2006

• Guest Professor at ETH, Zurich, Switzerland

2000 - present 

• A-rated “world leader” scientist rating from National Research Foundation, South Africa (international peer review process; (A1 upgrade in 2005).
• Visiting Professor in the Immunology Department at the University of Strathclyde, Glasgow, Scotland (extended to 2008).

2005

• Fellow for life at the University of Cape Town, South Africa
• Guest Professor at the Technical University ETH, Zurich, Switzerland
• Harry Oppenheimer Award for Sabbatical at the Biotechnology company Cytos AG & Technical University ETH, Zurich, Switzerland (price: 100000 US$)

Editor (2005/2006)

Editorial board

• F. Brombacher, (2004 – ongoing) NCB Immunology
• F. Brombacher, (2006 – ongoing) Parasite Immunology

Students graduated (2005/06)

2006

• 4 PhD-students
  Mosiuoa Leeto (coloured, male), Chesney Micherls (coloured, male), Anita Schwegmann (white female), Elmarie Myburgh (white, female)
• 4 MhC-students
  Thabang Mokgeti (Black, female), Jennifer Hoving (white, female), Michele van der Venter (coloured, female), Boipelo Sebesho (Black, female)
• 1 BsC (Hon)-student
  Mona Afshar (white, female)

2005

• 1 PhD-students
  Michael Drennan (white, male)
• 1 BsC (Hon)-student
  Helene Mearns (white, female)