Immunology of Infectious Disease Research Unit
Research highlights
Research by the Immunology
of Infectious Disease Research Unit has resulted in the following findings:
Interleukin-4
IL-4 is necessary for effective drug therapy in leishmaniasis
IL-4 is necessary for effective vaccination in schistosomiasis
Interleukin-12
IL-12 is crucial for protection against Chagas
A novel protective agonistic role of IL-12p40 in BCG and TB
Interleukin-13
IL-13 is crucial for worm expulsion
IL-13 has a protective function in chronic leishmaniasis
IL-13 is s major factor susceptible factor in allergic reactions
Tumor
Necrosis Factor
TNF-a and LT-a are crucial for protection in BCG and TB
IL-10 is important to prevent TNF-a-mediated toxic shock in Chagas. |
