Exercise Science and Sports Medicine Research Unit
The Molecular Biology and Genetics Research Group
Team
leaders: Dr
Malcolm Collins and Dr
Edward Ojuka
The research focus of
this group is to study the molecular mechanisms responsible for athletic ability,
exercise performance, susceptibility to exercise-induced injury, and disease
prevention
Selected research
areas:
- Genetic Basis of Athletic
Ability
- Does the exercise-induced
increase in GLUT4 gene expression involve dissociation of MEF2/HDAC5 complexes?
- The signalling mechanisms
in exercise induced increases in glucose transport and mitochondrial content
in muscle.
- The roles of AMPK,
CAMKIV and p38 as molecular intermediates in exercise induced GLUT4 biogenesis
- Exercise and glucose
uptake: Role of NRF-I in upregulation of GLUT-4 transporter protein and
mitochondrial biogenesis
- The effect of exercise
duration on CAMK and AMPK activities and HDAC5 trafficking in rat skeletal
muscle
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