Exercise Science and Sports Medicine Research Unit
The
Metabolic Research Group
Team
leaders: Dr
Julia Goedecke and Prof. Vicki Lambert
This research group has
evolved from a long-established history of cutting-edge research concerning
carbohydrate metabolism during prolonged, endurance activity. This work was
expanded in the 1990s and early 2000s to incorporate the study of lactate
metabolism in the aetiology of fatigue, substrate utilisation during endurance
activity, and the role of dietary fat, in altering the metabolic and hormonal
milieu during prolonged, ultra-endurance activity. More recently, this group
has undertaken research designed to identify individual variability of substrate
utilisation during exercise (as measured using indirect calorimetry), referred
to as a metabolic phenotype. In addition, we have developed techniques for
measuring mono-carboxylate transporters (MCTs), and are currently examining
the possible role of MCTs in explaining differences in substrate utilisation,
performance and lactate concentrations in runners of similar ability.
Selected research
areas:
- Effect of dietary
manipulation on metabolism and performance in athletes with different metabolic
phenotypes.
- Exercise performance
and mechanisms of fatigue associated with high-fat, CHO-loading dietary
regimen.
- Epinephrine infusion:
effects on substrate metabolism, muscle recruitment and effort perception
during low-to-moderate intensity exercise.
- The effect of ingestion
of a modified multiple carbohydrate mixture on RPE, taste perception and
gastric emptying rate during prolonged running
- Acute effects of recombinant
human IL-6 & CHO supplementation on IL-6 production and fatigue generation
during exercise
- The effect of dietary
intervention on the neuro-endocrine response, cognitive function and EEG
activity during insulin-induced hypoglycaemia
- Inter-individual variability
in metabolic(neuro-humoral) response to hypoglycemia and its effects on
cognitive & muscular fatigue and endurance exercise performance
- The effect of fatigue,
prior experience & metabolic perturbations on muscle recruitment strategies
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