Office of Malaria Research (MOMR)
Unit Director: Prof Rajendra Maharaj
Tel: 031 203 4851
Sunitha Kissoon (PA to Director)
Tel: 031 203 4852
The MOMR was given the mandate of supporting malaria elimination efforts in the southern African region. MOMR will primarily facilitate operational research aimed at assisting the National Directorate on Malaria to achieve its goal of eliminating malaria by 2020. The objectives of MOMR are to:
- Promote the MOMR’s administrative efficiency to maximise the funds available for research
- Synthesise evidence and influence the management of malaria eradication initiatives.
- Fund and facilitate basic and applied research to understand the social and biological determinants of health, as well as identify and develop novel interventions for malaria control.
- Develop the future cadre of malaria researchers
Collaborating Centre’s for Multi-Disciplinary Research on Malaria
University of Pretoria Centre for Sustainable Malaria Control (UPCSMC)
Director: Prof Christiaan de Jager
Tel: +27 (0)12 319 2191 / 2192
The University of Pretoria Centre for Sustainable Malaria Control (UP CSMC) is a fully integrated, multidisciplinary, interfaculty initiative. The aim of the Centre is to coordinate and promote collaborative research on safer and sustainable malaria control and management, to generate new knowledge. The Centre also aims to support new activities pertaining to safe malaria control in Africa through fundamental and applied research, supported by research collaboration with regional, national and international partners. Research activities of the UP CSMC are aligned with the National Department of Health’s goal to eliminate malaria in South Africa by the year 2018. The Centre’s vision is to make a substantial contribution towards the creation of a malaria-free Africa by: Employing sustainable and environmentally safe malaria control technologies; Establishing integrated vector management strategies; Ensuring effective malaria case management; and Promoting health education in affected populations.
In support of this vision, the UP CSMC has the following goals:
- to follow an integrated, trans-disciplinary approach in generating new knowledge pertaining to safe malaria control in Africa through fundamental and applied research;
- to support and promote research collaboration within the UP and with relevant partners regionally, nationally and internationally; and
- to build a critical mass of people performing cutting edge malaria research through the support of academic excellence and development of students.
University of Cape Town Collaborating Centre for Optimising Antimalarial Therapy in South Africa (C COAT)
Director: Prof Karen Barnes
Tel: + 27 (0)21 406 6294
University of Cape Town’s MRC Collaborating Centre for Optimizing Antimalarial Therapy (CCOAT) aims to maintain the human resource and infrastructure capacity to provide a multi-disciplinary platform for the conduct of studies to optimize antimalarial therapy and to grow the next generation of researchers that will continue its translational research programme. CCOAT has been conducting high impact, multidisciplinary field-based and hospital-based research in Africa for over 15 years. By informing the selection, dosing and use of antimalarial drugs, UCT has contributed to advancing national, regional and global efforts to control and eventually eliminate malaria. CCOAT’s focus on translational research on the clinical pharmacology of antimalarials that informs malaria treatment policy and practice including the comprehensive evaluation of changes in treatment policy and how these impact on antimalarial resistance, and optimizing dosing in vulnerable populations in order to delay drug resistance. C COAT’s translational research describes the continuum from drug discovery through to Phase 1 clinical trials to epidemiological surveillance, mathematical modelling and pharmacovigilance programmes to inform safe and effective deployment of antimalarial drugs to block P.falciparum malaria transmission.
Wits University Collaborating Centre for Multi-disciplinary Research on Malaria
Director: Prof Maureen Coetzee
The mission of the Wits Collaborating Centre is to strengthen South Africa’s National Malaria Control Programme through parasite and mosquito surveillance where the prevalence of molecular markers associated with lumefantrine and artemisinin resistance will be assessed in P. falciparum isolates. The Centre also determines gametocyte carriage in these isolates to help inform a primaquine drug policy. Furthermore, comparisons are made of different mosquito collection methods to determine the most effective methods to be used for routine surveillance. The Centre also investigates parasite-vector interactions in the laboratory using P. falciparum cultures. Infected mosquitoes are used to screen promising hit compounds.